Methods for testing statistical differences between groups in medical research: statistical standard and guideline of Life Cycle Committee
Seung Won Lee
Life Cycle 2022;2:e1
https://doi.org/10.54724/lc.2022.e1
ABSTRACT
In medical research, when independent variables are categorical (i.e., dividing groups), statistical analysis is often required. This situation mostly occurs on randomized controlled trials and observational studies that have multiple patient groups. Also, when analyzing continuous independent variables in a single patient group, breakpoints can be...
|
Regression analysis for continuous independent variables in medical research: statistical standard and guideline of Life Cycle Committee
Seung Won Lee
Life Cycle 2022;2:e3
https://doi.org/10.54724/lc.2022.e3
ABSTRACT
Variables measured in medicine are usually continuous, such as blood pressure, serum glucose, and drug dosage. There are statistical methods to confirm whether these variables act as independent variables that cause an outcome. Most of these methods are types of regression analysis. In this article, starting with a simple correlation coefficient, l...
|
PRISMA 2020 statement and guidelines for systematic review and meta-analysis articles, and their underlying mathematics: Life Cycle Committee Recommendations
Seung Won Lee, Min Ji Koo
Life Cycle 2022;2:e9
https://doi.org/10.54724/lc.2022.e9
ABSTRACT
The paper discussed the overall aspects of systematic review and meta-analysis and explored the main mathematical context of meta-analysis. This included various methods of analyzing the effect size and obtaining the average effect size depending on the variable type. In doing so, methods of obtaining effect sizes in continuous outcome variables, c...
|
Global, regional, and national incidence and mortality of COVID-19 in 237 countries and territories, January 2022: a systematic analysis for World Health Organization COVID-19 Dashboard
So Young Kim, Abdullah Özgür Yeniova
Life Cycle 2022;2:e10
https://doi.org/10.54724/lc.2022.e10
ABSTRACT
Objective: To estimate global, regional, and national incidences and mortality of the coronavirus disease 2019 (COVID-19) in 237 countries and territories since the outbreak of the COVID-19 pandemic to 31 January, 2022. Methods: Comprehensive estimates were produced through global, regional, and national studies of cumulative severe acute respirato...
|
Vaccine strategy against COVID-19 with a focus on the Omicron and stealth Omicron variants: Life Cycle Committee Recommendations
Lee Smith, Jae Il Shin, Ai Koyanagi
Life Cycle 2022;2:e5
https://doi.org/10.54724/lc.2022.e5
ABSTRACT
The Severe Acute Respiratory Syndrome Coronavirus type 2 (SARS-CoV-2), the cause of the pandemic of coronavirus disease 2019 (COVID-19), was first discovered in December 2019 in Wuhan, China, and was consequently transmitted across the world. Further, within a year of its initial discovery, vaccines against SARS-CoV-2 were developed using diverse t...
|
N-Nitrosodimethylamine-contaminated ranitidine and risk of cancer in South Korea: a nationwide cohort study
In Kyung Yoo, Dominic C. Marshall, Joo Young Cho, Hae Won Yoo, Seung Won Lee
Life Cycle 2021;1:e1
https://doi.org/10.54724/lc.2021.e1
ABSTRACT
Objective: On September 2019, the United States Food and Drug Administration announced that some ranitidine products were contaminated with unacceptable levels of N-nitrosodimethylamine (NDMA). We aimed to determine whether the use of ranitidine that was potentially contaminated with NDMA, rather than another histamine H2-receptor antagonist (H2 bl...
|
COVID-19 vaccines and coronavirus 19 variants including alpha, delta, and omicron: present status and future directions
Michael Eisenhut, Jae Il Shin
Life Cycle 2022;2:e4
https://doi.org/10.54724/lc.2022.e4
ABSTRACT
Coronavirus disease 2019 (COVID-19) is caused by a coronavirus, also called severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). It has caused urgent global health problems worldwide. The rapid spread of this pathogen, the development of its variants, and the escalating number of patients and their deaths prompted scientists to take up the...
|
Nationwide COVID-19 vaccination coverage and COVID-19 incidence in South Korea, January 2022: a national official report
So Young Kim
Life Cycle 2022;2:e2
https://doi.org/10.54724/lc.2022.e2
ABSTRACT
Objective: To reduce the risk of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, severe coronavirus disease 2019 (COVID-19) illness, and COVID-19 related death, all persons in South Korea should stay up to data with recommended COVID-19 vaccinations. This study investigated the rates and effectiveness of the COVID-19 vaccina...
|
Global, regional, and national COVID-19 vaccination rate in 237 countries and territories, March 2022: a systematic analysis for World Health Organization COVID-19 Dashboard, Release 2
Rosie Kwon, Masoud Rahmati
Life Cycle 2022;2:e15
https://doi.org/10.54724/lc.2022.e15
ABSTRACT
Objective: We aimed to better understand the impact of the COVID-19 pandemic through analysis of disruptions in a global, regional, and national status of COVID-19 vaccination coverage compared by a global scale, World Health Organization regions, World Bank income groups, and each country. Methods: Global datasets of 237 countries and territories ...
|
How serious is the Omicron variant? transmissibility, genomics, and responses to COVID-19 vaccines, and ‘Stealth’ Omicron variants
Yun Jung Choi, Krishna Prasad Acharya
Life Cycle 2022;2:e7
https://doi.org/10.54724/lc.2022.e7
ABSTRACT
Since its emergence on November 9, 2021, the Omicron variant has spread quickly across the globe as a new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and became the variant of concern at an astonishingly rapid rate. This new variant was found to be a massively mutated virus from the original virus formation. The World Health Organi...
|
