- About Life Cycle
- Life Cycle is an international, peer-reviewed, open access general medical journal and invites submissions of any original contribution that broadens, advances, or brightens medical science or practice, or that educates or delights the Journal’s readers. Building on the foundation of Life Cycle as the best science for medical health research, the Journal is committed to publishing high-quality and cutting-edge Original Research Articles, State-of-the-Art Reviews, and Letters that contribute to the advancement of healthy life from birth to senescence.
CURRENT ISSUE: Apr 2023, Vol. 3
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Obesity: lessons learned and the way forward
Life Cycle 2023;3:e6
https://doi.org/10.54724/lc.2023.e6 |
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Allergic diseases and COVID-19 pandemic: facing unprecedented challenges
Life Cycle 2023;3:e5
https://doi.org/10.54724/lc.2023.e5 ABSTRACT
The impact of COVID-19 on allergic diseases in adolescents is not well described. Although there has been a previous study that examined changes in prevalence one year into the pandemic, there is a need for follow-up due to the nature of the infectious disease. Therefore, this review article explored the extent to which the pandemic had a potential... |
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Age, ethnic, and sex disparity in body mass index and waist circumference: a bi-national large-scale study in South Korea and the United States
Life Cycle 2023;3:e4
https://doi.org/10.54724/lc.2023.e4 ABSTRACT
The study investigated age, ethnic, and sex disparities in body mass index (BMI) and waist circumference (WC) in South Korea and the United States. We conducted a bi-national large-scale study and analyzed data from the Korea National Health and Nutrition Examination Survey (KNHANES) and the National Health and Nutrition Examination Survey in the U... |
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The emerging epidemics in recent: mpox
Life Cycle 2023;3:e3
https://doi.org/10.54724/lc.2023.e3 ABSTRACT
In 2022, while the world has yet to be free from the aftermath of the long-term pandemic caused by COVID-19, the unusual epidemic of endemic diseases in Africa called mpox (monkeypox) was designated as the Public Health Emergency of International Concert by the World Health Organization, drawing world’s attention to whether new pandemic will occu... |
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The emerging pandemic recent: SARS-CoV-2
Life Cycle 2023;3:e2
https://doi.org/10.54724/lc.2023.e2 ABSTRACT
The coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), induces coughing, vomiting, or fever. The occurrence, duration, and severity of these symptoms vary from person to person, which makes symptoms of the COVID-19 infection ranging from those of a mild cold to death in severe cases. The cau... |
Effect of COVID-19 pandemic on vaccination and treatment pattern of prostate cancer: a comprehensive literature review, phase 2
Life Cycle 2023;3:e1
https://doi.org/10.54724/lc.2023.e1 ABSTRACT
During the COVID-19 pandemic, overall screening, diagnostics, and treatment have faced a downtrend, especially during the first wave and lockdown. Statistics showed improvements starting from the late era of the pandemic and the end of 2020. To improvise, the risk of delayed curative treatment was measured and treatment plans were amended according... |
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Methods for testing statistical differences between groups in medical research: statistical standard and guideline of Life Cycle Committee
Life Cycle 2022;2:e1
https://doi.org/10.54724/lc.2022.e1 ABSTRACT
In medical research, when independent variables are categorical (i.e., dividing groups), statistical analysis is often required. This situation mostly occurs on randomized controlled trials and observational studies that have multiple patient groups. Also, when analyzing continuous independent variables in a single patient group, breakpoints can be... |
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Regression analysis for continuous independent variables in medical research: statistical standard and guideline of Life Cycle Committee
Life Cycle 2022;2:e3
https://doi.org/10.54724/lc.2022.e3 ABSTRACT
Variables measured in medicine are usually continuous, such as blood pressure, serum glucose, and drug dosage. There are statistical methods to confirm whether these variables act as independent variables that cause an outcome. Most of these methods are types of regression analysis. In this article, starting with a simple correlation coefficient, l... |
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PRISMA 2020 statement and guidelines for systematic review and meta-analysis articles, and their underlying mathematics: Life Cycle Committee Recommendations
Life Cycle 2022;2:e9
https://doi.org/10.54724/lc.2022.e9 ABSTRACT
The paper discussed the overall aspects of systematic review and meta-analysis and explored the main mathematical context of meta-analysis. This included various methods of analyzing the effect size and obtaining the average effect size depending on the variable type. In doing so, methods of obtaining effect sizes in continuous outcome variables, c... |
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Global, regional, and national incidence and mortality of COVID-19 in 237 countries and territories, January 2022: a systematic analysis for World Health Organization COVID-19 Dashboard
Life Cycle 2022;2:e10
https://doi.org/10.54724/lc.2022.e10 ABSTRACT
Objective: To estimate global, regional, and national incidences and mortality of the coronavirus disease 2019 (COVID-19) in 237 countries and territories since the outbreak of the COVID-19 pandemic to 31 January, 2022. Methods: Comprehensive estimates were produced through global, regional, and national studies of cumulative severe acute respirato... |
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Vaccine strategy against COVID-19 with a focus on the Omicron and stealth Omicron variants: Life Cycle Committee Recommendations
Life Cycle 2022;2:e5
https://doi.org/10.54724/lc.2022.e5 ABSTRACT
The Severe Acute Respiratory Syndrome Coronavirus type 2 (SARS-CoV-2), the cause of the pandemic of coronavirus disease 2019 (COVID-19), was first discovered in December 2019 in Wuhan, China, and was consequently transmitted across the world. Further, within a year of its initial discovery, vaccines against SARS-CoV-2 were developed using diverse t... |
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N-Nitrosodimethylamine-contaminated ranitidine and risk of cancer in South Korea: a nationwide cohort study
Life Cycle 2021;1:e1
https://doi.org/10.54724/lc.2021.e1 ABSTRACT
Objective: On September 2019, the United States Food and Drug Administration announced that some ranitidine products were contaminated with unacceptable levels of N-nitrosodimethylamine (NDMA). We aimed to determine whether the use of ranitidine that was potentially contaminated with NDMA, rather than another histamine H2-receptor antagonist (H2 bl... |
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COVID-19 vaccines and coronavirus 19 variants including alpha, delta, and omicron: present status and future directions
Life Cycle 2022;2:e4
https://doi.org/10.54724/lc.2022.e4 ABSTRACT
Coronavirus disease 2019 (COVID-19) is caused by a coronavirus, also called severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). It has caused urgent global health problems worldwide. The rapid spread of this pathogen, the development of its variants, and the escalating number of patients and their deaths prompted scientists to take up the... |
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Nationwide COVID-19 vaccination coverage and COVID-19 incidence in South Korea, January 2022: a national official report
Life Cycle 2022;2:e2
https://doi.org/10.54724/lc.2022.e2 ABSTRACT
Objective: To reduce the risk of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, severe coronavirus disease 2019 (COVID-19) illness, and COVID-19 related death, all persons in South Korea should stay up to data with recommended COVID-19 vaccinations. This study investigated the rates and effectiveness of the COVID-19 vaccina... |
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Global, regional, and national COVID-19 vaccination rate in 237 countries and territories, March 2022: a systematic analysis for World Health Organization COVID-19 Dashboard, Release 2
Life Cycle 2022;2:e15
https://doi.org/10.54724/lc.2022.e15 ABSTRACT
Objective: We aimed to better understand the impact of the COVID-19 pandemic through analysis of disruptions in a global, regional, and national status of COVID-19 vaccination coverage compared by a global scale, World Health Organization regions, World Bank income groups, and each country. Methods: Global datasets of 237 countries and territories ... |
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How serious is the Omicron variant? transmissibility, genomics, and responses to COVID-19 vaccines, and ‘Stealth’ Omicron variants
Life Cycle 2022;2:e7
https://doi.org/10.54724/lc.2022.e7 ABSTRACT
Since its emergence on November 9, 2021, the Omicron variant has spread quickly across the globe as a new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and became the variant of concern at an astonishingly rapid rate. This new variant was found to be a massively mutated virus from the original virus formation. The World Health Organi... |