Table 1 Summary of trend in diagnosis of prostate cancer since the COVID-19 pandemic

Author, year Baseline Result Measure Period of interest (1) Result Period of interest (2) Result
Ip, 2021[17] 2018 to 2019 121,096,335 Physician attendances (including telehealth) 2019-2020 114,089,347 (6% reduction) 2020-2021 99,330,510 (18% reduction)
692,021 PSA tests 657,468 2020-2021 706,088
135,775 Free-to-total PSA tests 140,024 156,321
31,750 Multi-parametric MRI 35,672 35,942
19,923 Prostate biopsy 21,453 21,574
Ferrari, 2021[18], median (IQR) 2016 to 2019 283 (271 to 288) Vit D Lockdown (Mar to May, 2020) 66 (48 to 126)
146 (129 to 147) Total PSA 62% (median decrease)
2016 to 2019 256 (228 to 280) Vit D Post-lockdown 295 (267 to 322)
135 (116 to 151) Total PSA 181 (165 to 201)
Fallara, 2021[19] 2017 to 2019 2,285 Total cases 2020 1,458 (36% fewer)
Stroman 2021[20], number of centers Prostate MRI During the pandemic 14 (13%) centers stopped 39 (37%) centers offered with same indications 48 (46%) centers offered to selected high-risk patient group only
Before the pandemic 68 LATP During the pandemic 56
85 GATP 32
83 LATRUS 34
Surasi 2021[21], mean (SD) per week Before the pandemic 26.0 (26.0) Prostate MRI Lockdown period 11.6 (8.2) After lockdown 21.3 (25.3)
7.9 (11.7) Prostate biopsy 2.3 (3.3) 9.6 (8.0)
Pepe 2021[22] 2019 to 2020 2,000 Clinical office evaluation 2020 to 2021 1,015
351 Multi-parametric MRI 85
485 Prostate biopsy 201
187 (38.5%) Cancer diagnosis from biopsy 96 (47.7%)
Kaufman 2021[23], average monthly number Prepandemic 465,187 PSA tests Early Pandemic 295,786 (36.4% decrease) Late Pandemic 483,374 (3.9% increase)
659 PSA results ≥ 50 ng/mL 506 (23.2% decrease) 674 (2.3% increase)
1,453 Prostate biopsy results 903 (37.9% decrease) 1,190 (18.1% decrease)
182 Gleason score ≥ 8 130 (28.6% decrease) 161 (11.5% decrease)
Nossiter 2022[24] 2019 9,918/25,936 (38.2%) Transperineal/prostate biopsy 2020 10,592/16,551 (64.0%)
2019 32,409 Diagnoses 2020 22,419 (30.8% reduction)
Deukeren 2022[25] 2019 21,542 Diagnoses 2020 18,444 End of 2020 Restored to approximately 95% of expectation
13,621 (63.2%) N (%) of malignant pathology 12,756 (69.2%)
Abbreviations; IQR, interquartile range; PSA, prostate-specific antigen.